The Blenheim Rooms are less than 200 metres from the railway station.
Castelfranco Veneto is an important junction for main line trains from Treviso, Padua and Venice with connections to Verona, Milan, Bologna, Florence and Rome. There are also direct trains to and from Milan twice daily.

The nearest airport is at Treviso, just 25 km away, and Venice Marco Polo airport is only about an hour's drive. Verona and Brescia airports are also within a reasonable distance.

For those arriving by road, Castelfranco can be found where the trunk road from Treviso to Vicenza crosses the Trent to Venice and Padua road. The motorway system can be joined at Vicenza Nord, for Verona, Milan and the Brenner Pass to Austria and Germany, at Treviso for Belluno and the Dolomites and at Padua for Bologna, Florence and the South.